Food Allergens

Histamine Testing Solutions

Histamine is an organic nitrogenous compound that naturally occurs in the human body, serving crucial roles as a neurotransmitter, an immune response regulator, and a modulator of various physiological functions.

In an allergic reaction, the immune system releases elevated levels of histamine, leading to inflammatory responses that cause the characteristic symptoms of allergies. Individuals who are histamine intolerant experience similar reactions upon ingesting histamine-containing foods.

Histamine as a Marker for Bacterial Growth

Histamine production results from the decomposition of histidine due to the growth of specific bacteria in fish and certain other food products. Fish meal generated from materials that have been allowed to degrade before processing may contain high levels of histamine, posing a risk of toxicity.

High histamine levels in fish have been linked to numerous cases of poisoning, commonly referred to as "scombroid poisoning." This presents a significant health concern for consumers. To mitigate the risk of scombrotoxic fish, quality control measures necessitate the determination of histamine levels within a range of approximately 10 to 200 parts per million (ppm).

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Rapid and Highly Sensitive Histamine Test Kits

Romer Labs offers a comprehensive test kit portfolio featuring two highly sensitive enzyme-linked immunosorbent assays (ELISA) for the quantitative analysis of histamine in various food matrices. These rapid and accurate testing solutions ensure food safety and protect consumers from the adverse effects of histamine exposure.

ELISA - AgraQuant® Histamine Test Kit

AgraQuant® Histamine test kits are accurate and reliable enzyme-linked immunosorbent assays (ELISA) in a quantitative format. These test kits have been validated for the analysis of histamine in fresh fish, fish meal, cheese, sausage, milk, wine and champagne.

The AgraQuant® Histamine test kit is a competitive ELISAs in a ready-to-use format to reduce handling errors and comes with a set of 8 standards, a histamine coated plate, an acylation reagent, an acylation buffer, a wash buffer, a histamine antiserum conjugate, a substrate and a stop solution.

Results are measured with a specific ELISA reader, such as the StatFax® or the BioTek® reader.

ELISA - AgraQuant® Histamine Rapid Test Kit

The AgraQuant® Histamine Rapid test kits are specifically developed for the detection of histamine in fresh, canned and salted fish, as well as in fish meal and fish in oil. The workflow of these test kit has been optimized for fish samples and allows for a much faster assay procedure.

AgraQuant® Histamine Rapid test kits are competitive ELISAs in a ready-to-use format to reduce handling errors and come with a set of 8 standards, a histamine coated plate, an acylation reagent, an acylation buffer, a wash buffer, a histamine antiserum conjugate, a substrate and a stop solution.

Results are measured with a specific ELISA reader, such as the StatFax® or the BioTek® reader.

Our
histamine
test kits

AgraQuant^® Histamine

10002017

Allergens Histamine ELISA Quantitative

AgraQuant^® Histamine Rapid

10002018